Preprobradykinin-4

Entry Preprobradykinin-4
Uniprot code A0AEI4
Fasta A0AEI4
Peptide names T6-bradykinin Preprobradykinin-4 bradykinin V1,T6-bradykinin
Suborder Neobatrachia
Family Ranidae
Genus Hylarana
Species Hylarana guentheri
Ecozone Indomalaya
Distribution Central Vietnam throughout southern China (north to Yangtze River), including Hainan and Taiwan; introduced onto Guam
Antimicrobial & other activities contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells
Tissue Skin, Venom
Sequence MLTLKKSLLLLFFFGTISLSLCEQERDADEDENEQEAKVEDVKRAGYSRMIRRPPGFTPF
RIAPASSVKRNADEDENESRMIRRPPGFSPFRIAPASSVKRNADEDENESRMIRRPPGFS
PFRIAPASSVKRNADEDENESRMIRRPPGFSPFRIAPASSVKRNADEDENESRVARVPPG
FTPFRIAPEIV
Length 191
Signal peptide class Class-1
References:
2. for other activities T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis)


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MLTLKKSLLLLFFFGTISLSLC    
Prepro30 EQERDADEDENEQEAKVEDVKRAGYSRMIR   
BioactiveT6-bradykinin9NoRPPGFTPFR   
Prepro22 IAPASSVKRNADEDENESRMIR   
Bioactivebradykinin9NoRPPGFSPFR   
Prepro22 IAPASSVKRNADEDENESRMIR   
Bioactivebradykinin9NoRPPGFSPFR   
Prepro22 IAPASSVKRNADEDENESRMIR   
Bioactivebradykinin9NoRPPGFSPFR   
Prepro22 IAPASSVKRNADEDENESRVAR   
BioactiveV1,T6-bradykinin9NoVPPGFTPFR