Amurin-2

Entry Amurin-2
Uniprot code A0AAS2
Fasta A0AAS2
Peptide names Amurin-2 Brevinin-1PRa Brevinin-1CDYa Brevinin-1DYb
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana amurensis
Ecozone Palearctic
Distribution Western Siberia east to Sakhalin Island, northern and eastern Mongolia, northeastern China and North Korea, north to beyond the Arctic Circle (northernmost 71 degrees N)
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTLKKSLLLLFFLGTINLSLCEEERNADEEERRDDLEERDVEVEKRFLSLALAALPKLF
CLIFKKC
Length 67
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Regulatory Peptides 118 (2004) 135-141. A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro25 EEERNADEEERRDDLEERDVEVEKR   
BioactiveAmurin-220NoFLSLALAALPKLFCLIFKKC710013