Schmackerin-C1

Entry Schmackerin-C1
Peptide names Schmackerin-C1
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana schmackeri
Ecozone Palearctic, Indomalaya
Distribution Southern and south-central China in Henan, Shaanxi, Gansu, Sichuan, Guizhou, Hubei, Anhui, Jiangsu, Zhejiang, Hunan, Guangdong and Guangxi Provinces, at 200-1400 m elevation; reports from Vietnam and Thailand require confirmation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFPLKKSLLLLFFFGTISLFFFQEERNADEGEGEMTGEKVKKSILGTVKDLLIGAGKRAA
PRGGKGFFCKLFKDC
Length 75
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFPLKKSLLLLFFFGTISLFFF    
Prepro36 QEERNADEGEGEMTGEKVKKSILGTVKDLLIGAGKR   
BioactiveSchmackerin-C117NoAAPRGGKGFFCKLFKDC 54.227.1