Margaratain-B1

Entry Margaratain-B1
Peptide names Margaratain-B1
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana margaretae
Ecozone Palearctic, Indomalaya
Distribution Gansu, Guangxi, eastern Xizang, Sichuan, Hubei, Hunan, Guizhou, and southern Shaanxi, China, 390-1500 m elevation; mountains of northern Vientam (Lao Cai and Lai Chau provinces), 1900-2500 m
Antimicrobial & other activities antioxidant, inhibition of TNF-alpha production, stimulation of IL-8 production
Tissue Skin
Sequence MFTLKKSLLLLFFLGTINLSLCEQERDADEEERRCDPEERDVEVEKRFFSTSCRSGC
Length 57
Signal peptide class Class-1
References:
2. for other activities X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro25 EQERDADEEERRCDPEERDVEVEKR   
BioactiveMargaratain-B110NoFFSTSCRSGC