Margaratain-A1

Entry Margaratain-A1
Peptide names Margaratain-A1
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana margaretae
Ecozone Palearctic, Indomalaya
Distribution Gansu, Guangxi, eastern Xizang, Sichuan, Hubei, Hunan, Guizhou, and southern Shaanxi, China, 390-1500 m elevation; mountains of northern Vientam (Lao Cai and Lai Chau provinces), 1900-2500 m
Antimicrobial & other activities antioxidant, stimulation of IL-8 production
Tissue Skin
Sequence MFTMKKSLLLLFFLGIISLSLCEEERDANEEENEENGGETKVVEGKRVTPPWARIYYGCA
KA
Length 62
Signal peptide class Class-1
References:
2. for other activities X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLLFFLGIISLSLC    
Prepro25 EEERDANEEENEENGGETKVVEGKR   
BioactiveMargaratain-A115NoVTPPWARIYYGCAKA