Esculentin-1-OA1

Entry Esculentin-1-OA1
Peptide names Esculentin-1-OA1
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana andersonii
Ecozone Indomalaya
Distribution Northeastern India, Upper Myanmar, and northern Thailand to western Yunnan, China; south into Vietnam and Laos
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFPLKKPLLLIVLFGIISLSLCEQERAADEDEGSEIKRGLFSKFVGKGIKNFLIKGVKHI
GKEVGMDVIRVGIDVAGCKIKGVC
Length 84
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFPLKKPLLLIVLFGIISLSLC    
Prepro16 EQERAADEDEGSEIKR   
BioactiveEsculentin-1-OA146NoGLFSKFVGKGIKNFLIKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC 0.250.25