| Entry |
Dermaseptin 4 |
| Peptide names |
Dermaseptin 4 Dermaseptin S4 DS4 |
| Suborder |
Neobatrachia |
| Family |
Hylidae |
| Genus |
Phyllomedusa |
| Species |
Phyllomedusa sauvagii |
| Ecozone |
Neotropic |
| Distribution |
The Chacoan region of eastern Bolivia, northern Paraguay, Mato Grosso do Sul (Brazil), and northern Argentina |
| Antimicrobial & other activities |
antibacterial, hemolytic, antiprotozoa |
| Tissue |
Skin |
| Sequence |
|
| Length |
28 |
| References: |
| 1. for MIC/HC50 |
I. Kustanovich et al. / JBC 277 (2002) 16941-16951. Structural requirements for potent versus selective cytotoxicity for antimicrobial dermaseptin S4 derivatives; T. Jouenne et al. / Journal of Antimicrobial Chemotherapy 42 (1998) 87-90. Antibacterial activity of synthetic dermaseptins against growing and non-growing Escherichia coli cultures; R. Feder et al. / JBC 275 (2000) 4230-4238. Structure-activity relationship study of antimicrobial dermaseptin S4 showing the consequences of peptide oligomerization on selective cytotoxicity |