Brevinin-1Yb

Entry Brevinin-1Yb
Peptide names Brevinin-1Yb
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates yavapaiensis
Ecozone Nearctic
Distribution Formerly, low and moderate elevations in the drainage of the lower Colorado River and its tributaries in Nevada, California, Arizona, and New Mexico (USA), and central Sonora to western Chihuahuah, and extreme northeastern Baja California del Norte (Mexico). Now extinct over large portions of its former distribution
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence
Length 24
References:
1. for MIC/HC50 J.M. Conlon et al. / Toxicon 53 (2009) 699-705. Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis;  J.M. Conlon et al. / Comparative Biochemistry and Physiology, Part C 151 (2010) 313-317. Primary structures of skin antimicrobial peptides indicate a close, but not conspecific, phylogenetic relationship between the leopard frogs Lithobates onca and Lithobates yavapaiensis (Ranidae)


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveBrevinin-1Yb24NoFLPIIAGAAAKVVQKIFCAISKKC16253